The basis for this story is that the main character Nate is a police sketch artist for the NYPD. His works are so accurate that he seems to be almost psychic. One out of three of his cases are solved when he does the sketch work. As the book progresses the reader is treated to actual sketches of the criminals that he is in pursuit of.

Then Nate teams with a detective in an attempt to apprehend a White Supremacist murderer that feels he gets his order to kill straight from God. The killer is also an artist who begins to leave his work behind at the scenes of his murders.

Things become confused and Nate himself becomes a suspect because of the similarity of both artist works. In order to solve the crimes Nate turns to his grandmother, a native of Puerto Rico, who is also a Santeria or voodoo priestess for help.

Anatomy of Fear was a very unusual book with illustrations made by the author. The premise is different and a definite attention grabber. The clues are many but beware of red herrings left along the way to make the reader think.